Michael Conforto and David Villar hit back-to-back home runs in the second inning, Luis Matos hit a tiebreaking solo shot in the fifth and the San Francisco Giants beat the Chicago Cubs 4-3 on Wednesday night. Seiya Suzuki homered for Chicago, which lost its fourth in a row and fell to 3-13 in its last 16 road games. Giants starter Hayden Birdsong was called up from Triple-A Sacramento for his major league debut, and allowed three runs and six hits with five strikeouts and three walks in 4 2/3 innings.