Blake Snell earned his first win for the San Diego Padres, backed by Manny Machado's early three-run homer in a 6-2 victory Saturday over the San Francisco Giants. Pinch-hitter Jurickson Profar connected on a solo homer in the eighth inning and Jake Cronenworth added a two-run single as San Diego pulled away. Snell (1-0) gave up one earned run and five hits in five innings, striking out six.